Activities
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Director Director : Activity The Experimental Research Laboratory owes its existence to the culture of innovation at the CCML: "The goal of the Association is to develop, using any means necessary, the possibilities of chest and cardiovascular surgery, to promote progress in all forms of surgery, and to foster the methods of tomorrow" (Article 1 of the statutes of the Marie Lannelongue Association 1948).
The first research work of Dr. Juvenelle on moderate surface hypothermia led to the first intracardiac operations and was followed up by that of Professor Charles DUBOST in 1955 on the first artificial heart-lung, a central element which would lead to the operative technique of extracorporeal circulation (at normal or low temperature). Ever since then, the Experimental Research Laboratory has always attracted motivated surgeons and scientists, fascinated by both the clinical and the academic aspects of the questions raised.
From the beginning of the 1960’s, one of the Laboratory’s main research interests has been the development of lung and heart-lung transplantation with, at the beginning of the 1980’s, the establishment of new, promising techniques. This led, in 1985, to the first heart-lung transplantation procedures in Europe by Professor Philippe DARTEVELLE, carried out at the CCML.
All the research of the Experimental Research Laboratory is incited by clinical problems seen on a daily basis by the CCML surgeons and clinicians: this close relationship with the multidisciplinary surgical research unit affords the CCML physicians a unique resource that is central to maintaining our sustained quest for excellence and innovation.
Surgical research activities break down between three broad, inter-related topics:
The development of experimental models to reproduce human diseases as faithfully as possible.
The use of these models to investigate mechanisms underlying these diseases.
The development of surgical techniques to treat them
To achieve these ambitions, the Experimental Research Laboratory has a team that specialises in anaesthesia and surgical research together with a full surgical facility (operating theatres, an angiography room, surgical equipment, extracorporeal circulation equipment, etc.) comparable to the resources allocated for clinical surgery.
This Laboratory is affiliated with the UPRES EA 2705 Unit. |